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BRL 44408 maleate
CAS No. 681806-46-2
BRL 44408 maleate ( BRL44408;BRL-44408 )
Catalog No. M15602 CAS No. 681806-46-2
A potent, selective α2A-adrenoceptor antagonist with Ki of 1.7 nM, 80-fold selectivity over α2B-adrenergic receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameBRL 44408 maleate
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective α2A-adrenoceptor antagonist with Ki of 1.7 nM, 80-fold selectivity over α2B-adrenergic receptors.
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DescriptionA potent, selective α2A-adrenoceptor antagonist with Ki of 1.7 nM, 80-fold selectivity over α2B-adrenergic receptors; significantly increases stimulated noradrenaline release in rat locus coeruleus slices at 0.1-1 uM, significantly increases the electrically induced release in rats.
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SynonymsBRL44408;BRL-44408
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PathwayAngiogenesis
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TargetAdrenergic Receptor
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RecptorAdrenergic Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number681806-46-2
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Formula Weight331.37
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Molecular FormulaC17H21N3O4
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Purity>98% (HPLC)
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Solubility——
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SMILESCC1N(CC2=NCCN2)CC3=C1C=CC=C3.O=C(O)/C=C\C(O)=O
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Chemical Name2-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-2,3-dihydro-1-methyl-1H-isoindole maleate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kiss JP, et al. Brain Res. 1995 Mar 20;674(2):238-44.
2. Callado LF, et al. Eur J Pharmacol. 1999 Jan 29;366(1):35-9.
3. Young P, et al. Eur J Pharmacol. 1989 Sep 22;168(3):381-6.
2. Callado LF, et al. Eur J Pharmacol. 1999 Jan 29;366(1):35-9.
3. Young P, et al. Eur J Pharmacol. 1989 Sep 22;168(3):381-6.
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